Publications

P M Brown, J A Ezekowitz (2018). Examining the Influence of Component Outcomes on the Composite at the Design Stage. Circulation: Cardiovascular Quality and Outcomes.

P M Brown, J A Ezekowitz (2018). Frailty modelling for multitype recurrent events in clinical trials. Statistical Modelling.

P M Brown, J A Ezekowitz (2017). Power and Sample Size Estimation for Composite Endpoints: Practical Implementation using Data Simulations. Journal of Modern Applied Statistical Methods.

P M Brown, J A Ezekowitz (2017). Multitype Events and the Analysis of Heart Failure Readmissions: Illustration of a New Modeling Approach and Comparison With Familiar Composite End Points. Circulation: Cardiovascular Quality and Outcomes.

P M Brown, J A Ezekowitz (2017). Letter Regarding Article: “Development and Evolution of a Hierarchical Clinical Composite End Point for the Evaluation of Drugs and Devices for Acute and Chronic Heart Failure: A 20-Year Perspective”. Circulation.

P M Brown, J A Ezekowitz (2017). Composite End Points in Clinical Trials of Heart Failure Therapy. How Do We Measure the Effect Size?. Circulation: Heart Failure.

P M Brown, J A Ezekowitz (2016). Composite End Points in Acute Heart Failure Research: Data Simulations Illustrate the Limitations. Canadian Journal of Cardiology.